PROSPECTIVE STUDENTS
Changing Demands in Research: Student Perspectives at UTMB
How these essays came to be…

Neuroscience

Luis Felipe Orozco Cabal, M.D.

Education: committing to embrace the difference September 2004:

The true gift of education is most salient in its ability to endow us with the power to shape our lives according to what we have learned. Knowledge enlightens the person by increasing his capacity to perceive reality from different perspectives. Hence, education leads to the inevitable acceptance of differences and uncertainties as a normal component of the social and natural environment we live in. To prepare people to embrace the difference or “otherhood” should be the most important objective of anyone or any institution devoted to teaching. As Edgar Morin (2001) stated: “We should learn to navigate on a sea of uncertainties, sailing in and around islands of certainty”[1]. Consequently educating is above all a moral responsibility and a life time commitment.

Early in my life I had the good fortune of knowing persons who had made of this predicament their entire life. My father among them showed me the beauty of pursuing the truth through science and preparing to help others find their own “truths”. His teachings and those of other visiting professors, who built together the French and German philosophical schools of the late twentieth century, motivated my decision to become a scholar and researcher.

While I was attending medical school I became fascinated with the neurological and psychiatric patients and the existent theories regarding the central nervous system information processing functions. More specifically, I became interested in the neurobiology of human consciousness, a question that still remains as my long term research goal. In those days, research opportunities were limited in Colombia. The best option I had was to begin additional training in those jobs on which I could acquire a broad scientific knowledge that could serve as foundation for a further solid formal training in basic neurosciences. Near graduation, I traveled abroad to receive further training in clinical neurophysiology. Doing this clerkship under the supervision of Dr. David Ingram and others at the Saint Bartholomew’s Hospital in London, gave me the opportunity of understanding the real differences between Medicine and Basic Sciences research. After several conversations with Dr. Pamela Prior, Dr. David Ingram and Dr. Steve White, it was clear to me that to fulfill my expectations as a person and to obtain the knowledge necessary to approach the human brain, I needed to go back to graduate school and work on a Ph.D. In addition, another observation influenced my recent decision. The thought process behind medical decisions is very different from the one needed to approach problems within basic sciences. They give the impression of being two non-exclusive synthesizing streams of thought, and I desired to be educated in both.

During the following months after my return from London, I began the process of applying to various graduate schools. The application process was at sometimes frustrating. The first year I applied mainly to British and German neuroscience programs. I was enchanted by the European student life and by the form and rigor of their training programs. That year I did not had very good luck with my applications. Fortunately a few months after, I was offered a position as instructor professor in the Anatomy Department of the Medical School I had graduated from. I happily accepted the position. This experience would give me a better chance of being accepted in a doctoral program the following year. Later that year I started the application process for a second time, but on this occasion I included several American institutions, among which was UTMB’s Neuroscience program. The criteria I used to choose the institutions to apply to included:

  1. The institution is committed to promoting diversity among their students and Faculty.

  2. The Graduate School, Department and Program strongly favor student development and good mentoring.

  3. I needed an introductory year to level out with my peers. This was a must since my background was very strong in clinical training but less in basic sciences and research.

  4. The program had to be affiliated to a Medical training program. In this context, having a medical background was an extra benefit and not a defect.

  5. The Faculty in the program had to be strong in the fields of electrophysiology and neurophysiology.

  6. The University and the Graduate School were interested in preparing people for life as well as for science. They had to see and treat students as a whole.

  7. Graduate students received economical support through out their doctoral training.

The second time I got accepted to three programs: UTMB, The Institute of Psychiatry in London and Universidad Autonoma de Madrid in Spain. I couldn’t have been more pleased. The offer that struck me the most was the one from the Neuroscience program at UTMB. The other two programs offered very little or no economic support, they were not so strong in electrophysiology and invertebrate neurophysiology, and demonstrated to be less student-oriented. In contrast, UTMB Neuroscience Department had excellent electrophysiologists and invertebrate neurophysiologists among its Faculty, offered a decent stipend, and demonstrated interest in knowing about me both as a person and a potential scientist. The telephone interview with the program director was a deciding factor in my decision to accept UTMB’s offer to enter the program. First, I was not expecting the program director to call me at my home . Second, he was very clear from the start on what the program expected from a doctoral student and the program’s philosophy. Third, I was treated as equal and gave me the necessary time and attention to freely communicate my concerns and thoughts about doctoral education and the program. Lastly, upon reading his web page, I found that the program director himself has been an example of scientific excellence and commitment to Academia throughout his career. This last point was essential in my decision to enroll in this program.

One month after the telephone interview with the director I received the acceptance letter. I could not believe it! Being able to travel abroad to work on a Ph.D. degree is a privilege by any standard, but especially in light of the limited educational opportunities available to most people in my home country. In Colombia according to Colciencias (2004), the most education any average young individual can expect to receive through out his or her entire life is only of three years of primary school. Only 17 of 100 individuals between the ages 19-23 are admitted and are able to study in an advanced education institution. Even more alarming is the fact that only four of these 17/100 individuals who make it to the Universities graduate from them. Of these four, less the than 1/100 (0.3%) is accepted to and finishes a Ph.D. But the problem is even more complex. From the 89,000 university professors in the country only 2% have a PhD. This means that even if accessibility to higher education institutions is secured by the State, the number of highly educated professors is insufficient to cover the needs of the system. Therefore, it is important to realize that earning a Ph.D. not only represents an exciting personal challenge, but also, brings with it an enormous social responsibility. It is the duty of those who “know” to foster opportunities for younger generations and for their countries. Everyone should have the liberty and the chance to receive a good education. It is in this lack of opportunity where we see the true solitude of Latin American countries. It did not take a long time to respond to UTMB’s offer and to communicate my acceptance to the program coordinator. I was assigned a senior student to help me out with any doubt I had. This was especially important considering my status as a foreign student. Though international moves can be overwhelming, my arrival in Galveston was not a major problem. With information provided by the senior student and the program coordinator I had already arranged a place to live and an estimate of the amount of money required to live for the first few months. This experience was not the same for all the students. Some American and international students had a rough time adapting to their new environment.

The first year in graduate school was difficult. The depth with which the courses are taught makes people realize how daunting the goal they have committed to is. Science is becoming just as complex as the problems it studies. It is necessary that scientists speak both a particular as well as a common language. In 1922 Weber writes: “In our time, the internal situation, in contrast to the organization of science as a vocation, is first of all conditioned by the facts that science has entered a phase of specialization previously unknown and that this will forever remain the case. Not only externally, but inwardly, matters stand at a point where the individual can acquire the sure consciousness of achieving something truly perfect in the field of science only in case he is a strict specialist”[2]. This statement still holds as valid, but with one caveat: science specialists without a solid basic science foundation are technologists. It is the obligation of the Institutions to recognize and act upon this reality.

One of the most important aims of doctoral education is shaping the intellect for continued, critical and profound syntheses through systematic observations. In this context, the first year curriculum is necessary because it allows the students to acquire the basic vocabulary of science and a certain special “modus operandi”. It is difficult to comprehend that although scientific problems are diverse and variable, science in essence remains unaltered, because of the constant nature of its intention. Science is after all, having a particular attitude towards the world.

One frequent criticism from the students is that most of them have carried these same courses during their undergraduate studies and therefore think they are wasting precious time. This raises the question if people should be allowed to decide whether or not to take these courses. Against a favorable answer to these concerns lays the heterogeneity of the BBSC student’s background. The BBSC is a way of unifying concepts and ameliorating differences among students.

Once we have finished the core courses, we are allowed to take more specific courses according to our interests. There appears to be an enormous gap between the major courses and the modules. Some attention should be placed on the depth with which these modules are taught. Some of them are perceived as superficial and disorganized. This is frustrating at times because people are interested in knowing how a series of problems within a particular field of interest have been approach. Modules serve to orient vocations and some of them even after declaring a program seem vague and superficially taught. From my perspective, these courses should be constructed in such a way that the students learn in depth the basic principles underlying sets of common phenomena within a field (e.g., neuronal networks, muscular contraction, orientation and locomotion). In addition, at times poor coordination and communication among the faculty teaching a module has resulted in a decrement of the quality and coherence of the lectures. How important is that the professors are really committed to the courses they teach. Commitment not only signifies starting each class on time and preparing the material for the lectures, but also believing that students can always do better, allocating sufficient time to answer to their questions, organizing the lectures according to a particular structure, sharing what each faculty lectures on, and having continuity. The students should never receive the message, explicitly or implicitly, that being an average student is fine. These are some problems that can be improved.

Personally, choosing a department was not a major problem because I knew with certainty the field I was interested in. Nonetheless, after weighing my options I chose to stay in Neurosciences because the philosophy and alumni profile promoted by the department matched my own interests and perspectives. I wanted a department that understood the importance of having constant and high quality courses, a department that was student-oriented, one that believed in treating the student as a whole, and above all, one which believed that building a firm basic scientific foundation is the best way of assuring a strong specialization process. Most of the major areas in neurosciences are covered within the program’s required courses. Unfortunately, less diversity is found among faculty research interests. To partially solve this deficiency, department chairs and program directors should coordinate efforts to advertise the courses offered by their respective programs and the types of research interests other faculty members have. This lack of diversity is also noticeable in the topics addressed by our seminar speakers. Usually our guests are specialists in the same topics on which our professors work. This may result in some redundancy. As students we also need to meet experts that work on research fields different from our own areas of expertise.

Diversity of interests among faculty would also make it easier to find a lab that accommodates our personal and professional needs. Choosing the right mentor is one of the most important decisions that a graduate student has to make by the end of the second year. The Orientation in Science sessions were vital to meet faculty and learn about their work. It was also a very good opportunity to talk to older students and to identify common research interests. Nonetheless, some times mistakes are made in choosing a lab and a mentor. Two years ago I choose a mentor based on his academic records, his scholarly excellence, the type and number of publications of the lab per year, the experience of former and current graduate students and postdocs, and his research interests. I took into account the mentor’s professional skills. I never questioned myself about our personalities. Mentoring is more than just accepting a student and giving him a project and funding. As graduate students, we choose our mentors because we identify with what they are; we find in them a model to follow. Concordantly, in most traditional British universities, students stand in line beside the Professor holding his toga waiting for him to turn around and listen to their question. Similarly, in medical school it is common to see how the rounds pass by the hospital wards with a group of professors walking in front followed by a group of students. Why do students walk or stand behind their professors? It is not because they are shy or apologetic, or because the professor walks faster than the young students. It is because the professor represents what is to be followed, all we want to know and our most immediate figure of authority. As students we respect who they are as a whole. Their job transcends the verbal transmission of scientific facts. A very honorable professor recently said to me: “People do not realize that receiving a graduate student in their labs is a moral responsibility”. Later he added: “I am here to secure you whenever you feel insecure”. How important is it that the mentor assumes his role as a guide with willingness and pride. I made the mistake of not asking these questions. There are labs whose atmosphere is simply not adequate, despite an excellent number of publications.

Ending my second year in the program, I had completely lost enthusiasm and faith on the research I was carrying on. I decided to switch mentors. This was not an easy decision but I do have to say that I was never left alone by the department or the faculty. They were always supportive, doing everything possible to make the transition between labs easier. I interviewed with other professors and took what I believe was a more informed decision.

I joined my new lab near the time of the qualifying exam. I soon found that these require months of preparation. From a personal viewpoint the content and depth of the exams is adequate. While taking the exams, it was frustrating at times, to feel that you ought to know more. For some they even serve as a good wake-up call. To excel in them brings great relief.

I am now starting my third year in the program and preparing to defend my dissertation proposal. In these past few months I have felt comfortable delineating my project for the next three or more years. Again, I realize the importance of good mentoring. Writing the proposal seems like a daunting task but I feel that having a strong mentor willing to work with me along the way makes an immense difference. This is especially true in the event that something does not work quite as planned, as often happens in research. In sum, after these last three years, I reaffirm my desire to be part of this program and institution. It has definitely made me a better person and a better scientist.

[1] Morin, Edgar. 2001. Seven Complex Lessons in Education for the Future. Education on the Move. Paris: UNESCO

[2] Weber, M. (1922).'Wissenschaft als Beruf,' Gesammlte Aufsaetze zur Wissenschaftslehre.Tubingen; P. 524-55. Available at URL: http://www2.pfeiffer.edu/~lridener/DSS/Weber/scivoc.html.

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Erica Schwartz

Excited by the idea of becoming a scientist, my interests in pursuing graduate studies did not intensify until after my undergraduate education and research experience. I entered college like the majority of other science oriented students; I decided to be “premed.” I took the standard courses ranging from organic chemistry to physics and loved every minute of them. However, during my junior year the time came to start applying to medical schools. I took the first step in taking the MCAT and then began to apply for applications to various schools. The applications began to multiply in number on my desk and I could not bring myself to complete them. I started to become confused because this should be exciting and something I have wanted to pursue since I was a small child, right? This is when I began to think that maybe I only thought this was what I wanted because I never exposed myself to any other options. I thought it would be an excellent idea to take a year off after graduation and make sure medical school was the correct path for me to pursue. Therefore I thought that getting a job in the research field would still allow me to be in the science field and to try something new. After one year I discovered my passion was for research. I gained a lot of confidence in my ability to adapt to new environments and learned techniques that I had never encountered. I also learned a great deal about the nature of research and the lifestyles of researchers. When I became familiar with the amount of dedication and hard work essential to project advancement, I was more focused on my goal of becoming an excellent researcher. During my two years working I was not a stranger to the frustration and disappointment inherent in research work, and I was spurred on by the thrill of discovery. I found a great deal of enjoyment working in research and realized that research is merely the stepping stone to medicine.

During my two years of research, I took an interest in the field of neuroscience. From this, I decided to apply to graduate school taking the necessary steps to pursue a doctoral degree. While applying to graduate schools I began to see that the area of neuroscience is smaller than other programs and the programs I looked into varied quite a bit. I applied to a variety of schools all over the country and to be quite honest UTMB was my last choice. It was not my last choice because of the school itself, I believe it was because of the location. UTMB was the first graduate school I visited and it was fairly early on in the whole interview process. Following my visit at UTMB I visited 5 other graduate schools ranging from the west coast to the east coast. Every single time I was at another school I never felt like I was wanted or that the faculty was interested in my ideas or my area of interest. A lot of the programs I visited were very small, meaning that the only students you socialized with were in your program. UTMB sparked my interest due to the BBSC program because it allowed the opportunity to be among fellow peers in different fields and also to make sure the program you were choosing was in fact the right one for you. The idea of not having to declare until the end of your first year after going through different lab rotations made the decision so much easier. The faculty at UTMB were so warm and so accepting of new students and new minds. During the interview process they never made you feel as if you were being “interviewed.” The faculty automatically made you feel as if you were already part of the UTMB family. I never felt like I was being judged, as I did at other schools. I was very impressed by the interactions between the students and the faculty. The students were very friendly with the faculty and vice versa. The faculty seemed to truly care about the students and their research wanting them to see that science is now in their hands. The faculty and the students were honest and upfront about the pros and cons of UTMB. They did not put up a façade trying to “sell” the school to me. They made it quite clear that is was my decision and one that I need to make sure is good for me. The faculty made it perfectly clear to me that UTMB is not for everyone and I have to go where I feel 100 percent comfortable. Hearing that made my decision so much easier in the end because I finally saw that UTMB is not choosing me but I am in fact choosing them. Therefore, when the acceptance letter came from UTMB I knew right away that I wanted to go there and didn’t care about any of the other schools I visited. When I accepted my parents asked me many times if I was sure I was making the right decision, since this was not my first choice before I visited, I told them I have never been more sure.

UTMB’s first year is very different from the other programs I was interested in because of the BBSC. I was not sure what to expect from the BBSC and not sure if I would enjoy taking the required classes all over again. Having completed the BBSC I believe it is very necessary and allows you to continue on into whatever field you choose; however, I think the structure could use some fine tuning. I felt like the depth and difficulty of these classes was appropriate and never felt the material was beyond my scope of learning. However, I felt that I had to teach myself a lot of the material because the professors did not always teach the main concepts. It seemed at times the material that was mainly focused on in lecture did not reflect the exams all the time. I did feel that there were some professors who did an excellent job instructing and did care about the students understanding of the material at hand. I did not like how lectures seemed to be rushed at times and some of the professors did not know the answers outside of their power point presentations. Overall, I would say that the core class MBG was better taught than the other two core classes, biochemistry and cell biology. One thing I would improve on in biochemistry is making the problem set discussion groups more similar and monotonous. I experienced a facilitator that diverted a lot from the subject at hand and therefore I was at a disadvantage when it came to exams and my grade overall. I think the problem set discussion should just be with everyone as it is in MBG. However, overall I think the BBSC is a good thing. I believe that it allows the transition into graduate school to be less stressful and is a good stepping stone into the program of your choice.

I declared neuroscience as my department simply because that is why I chose UTMB. I knew from the beginning that I wanted to enter this field of research because I had previous experience in this field. I cannot comment on the departmental specific curriculum as of yet because I have only taken one class. Presently, I am in the main neuroscience class and feel that it is more than I expected in my graduate curriculum. It is a very demanding class but yet so interesting. It is going to be very beneficial in my chosen area of research and something that I will need for my career in the future. At the beginning I felt like the neuroscience program curriculum is more demanding than other programs at this university; however; the knowledge I have already gained is indescribable. Over the course of the next year I will take many more of the neuroscience classes and then can have a better understanding of the curriculum.

Once I chose the program I wanted I needed to choose the lab I wanted to matriculate into. I chose the lab I am in now because of my mentor and the area of research I wanted to do. While looking for a lab I first looked at the research the investigator did and then what my interaction was with him/her. I knew the relationship I had would be very important and most likely play a part in receiving my degree and continuing on with my research in the future. I also looked at the dynamics of the lab. I wanted to feel comfortable with the other students and other people that worked in the lab. This was very important to me because one of the labs I was in the people in the lab were not friendly to me at all. I was the only female in the lab and English was not their first language. They would not address me and I always felt like they were talking behind my back. I really enjoyed the investigator and the research he did, but knew that the dynamics of the people in lab might be more important. You spend a huge majority of your time with the people in your lab and if you are not comfortable in your working environment obtaining your degree will not be an enjoyable process. Another thing I looked for was how receptive my mentor would be of my ideas and how they would let me run with them, meaning was I able to come up with my own ideas or did I only have to listen to what he/she said. Therefore in the end I chose the lab I felt most comfortable with, where I believed I would be able to succeed in the research, where I had the most interest in my project, and where the mentor was just as excited as I was to be in the lab. I liked the other labs I rotated in; however, they were just not the right fit for me. Yet, I do believe that I learned many techniques from these other labs and made some great relationships that will help me in the neat future.

Since I just started my second year, I am just getting my feet wet in the whole precandidacy experience. From what I have experienced so far I am very happy at UTMB and glad I chose this place to undergo my graduate school experience. I am very excited yet nervous at the same time to further my studies towards the qualifying examination and finally towards my dissertation. However, I just have to wait and see how it all goes and just sit down and enjoy the ride.

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Michael Scott

My decision to go to graduate school came two years after I graduated from Fort Lewis College, a small liberal arts college in the San Juan Mountains of southwestern Colorado. At the time of my decision, I was working as a technician in a lab at the University of Colorado Health Sciences Center in Denver, studying the genetics of alcohol consumption. This was my first real experience in research. My undergraduate institution offered little in the way of research experience, and none in the area that I would become interested in, which would be neuropharmacology. I found that I enjoyed research and felt at home in a laboratory setting. During my time at UCHSC, I interacted with graduate students and saw their freedom to express creativity in their research. I, however, as a technician, would perform radio ligand binding experiments, and hand off the results to another technician for analysis, never to be involved in any subsequent academic discussion. After a year, I decided to apply to graduate school.

I interviewed at a few schools and realized that my application was perhaps not strong enough to be accepted into the programs that I preferred. I was accepted into a Ph.D. program in anatomy at the University of West Virgina, and a master’s program in biology at the University of Minnesota at Duluth (UMD). Since anatomy was nowhere near my area of interest (my application must have been passed on to the department), I chose the latter. At UMD, I was able to study regulators of catecholamine release, and bolster my application for a new round of interviews.

I submitted my application to a few neuroscience programs. Besides UTMB, I was accepted to the neuroscience programs at the University of Minnesota, and the University of Iowa. Ultimately I chose UTMB, because of the number of faculty doing research that I was interested in. I felt that there would be at least three faculty members that I could seriously consider choosing as a mentor. Additionally, the experience that I had while interviewing at UTMB gave me enough opportunity to have thorough discussions with faculty and candid discussions with current graduate students. At some of the other interview sessions that I attended, I had some negative interactions with faculty members. At UTMB, I felt that the faculty was dedicated to providing a nurturing environment where I could receive my graduate training. I felt confident that I had received an as objective as possible description of the neuroscience graduate program at UTMB.

The neuroscience program at the University of Iowa accepted me prior to my interview with them, so I immediately knew that I had a very attractive opportunity before I interviewed with other programs. UTMB sent me a letter of acceptance about a month after I interviewed. I appreciated the promptness of the offer of admission. It gave me the impression that UTMB was serious about students and academia in general.

My first year at UTMB was just as described during the interview process. I was warned that the BBSC was still in its early stages. I found that it still had some kinks to work out. In terms of breadth, rather than a survey format, the BBSC covered concentrated areas of expertise. This was because lecturers gave a few lectures in their areas of interest, and submitted test questions. I found that I studied many narrow topics in great detail. This approach left me feeling like I had received a restricted review of cell biology and biochemistry, not necessarily a wide understanding which may have been a more favorable foundation with which to begin my graduate training. However, once I had progressed through the BBSC, and into the neuroscience modules, the topics covered and depth were extremely helpful in preparing me for subsequent aspects of graduate school. I felt that the difficulty level of the courses in the BBSC was appropriate for a first year graduate level.

I chose the neuroscience department predominantly because of the large number of faculty and students associated with it. I also felt that the program coordinator took a vested interest in each of the students in the program. I felt that the neuroscience program would provide a broad groundwork for my graduate training.

I chose to do rotations with faculty who were studying neuropharmacology and behavior. My experience during rotations was invaluable in deciding which lab to join. Both of the 12 week rotations that I did were positive, interesting, and educational. I was able to see how different labs were run in the same university. I was fortunate that both faculty members allowed me input into the “rotation project” that I worked on. Choosing a lab was extremely difficult. I was interested in both labs, and seriously considered them both. I didn’t have to make any concessions as far as choosing a research project or mentor. My relationship with the mentor of the lab that I didn’t decide to join is excellent. In fact he is serving on my thesis committee.

The courses that I took during my first year and a half, particularly the modules that were organized by the neuroscience program more than prepared me for the qualifying exam. However, due to the required coursework, I wasn’t able to spend much time in the lab prior to taking the qualifying exam. At one point during my second year, I was taking three courses at once. It would have been nice to be able to spend more time in the lab thinking about possible research projects and trying out different techniques to go about answering the scientific question. I was satisfied with the experience of defending my research proposal. I felt that I received valuable insight and suggestions regarding my proposal. However, I would have liked to have more preliminary data so that my specific aims would have had a stronger basis. In general, the process of entering candidacy was a positive one, and I felt like I was well-supported by my mentor and graduate program.

I feel like I have a good relationship with the other students in the program. I have a group of close-knit friends who are also in the neuroscience graduate program that I spend time with socially. Generally, the faculty in the neuroscience program are accessible and easily approachable. I have a great relationship with the program director. I know that I can meet with him at anytime regarding any issues that may come up during my training.

In the lab, I receive much guidance with my mentor. I meet with her a few times a week to discuss experiments and data. I am extremely satisfied with my relationship with my mentor. In the laboratory, there is absolutely no shortage of resources. I have my own desktop computer for writing and data analysis and another for electrophysiological data acquisition. All of the equipment required for the proteomic aspect of my project is also available in the lab. I am very happy with the availability of guidance and equipment. I have never regretted my choice in lab or thesis committee members, so I have never considered changing either. I have the support that I need to realize my potential as a graduate student.

My project involved performing an initial proteomic study, and as a result, progress was a little slow at the beginning. I feel that the amount of publications that I have currently is not a true reflection of the work that I have done. In the future, I feel that my publications will “catch up” and truly reflect the work that I have done.

I have received much valuable input during my annual committee meetings. The meetings have turned out to be very helpful in determining the most effective directions to take in my research. There have been no problems during any of the meetings.

Overall, I have a minimal amount of interaction with the Dean’s office and other GSBS administrative personnel. During my first year however, I found the GSBS program coordinator to be incredibly helpful. Any issues I had with classes and registration for classes were quickly and efficiently resolved.

After I graduate, I’d like to do an academic post-doc. I hope to always stay close to the lab bench. Eventually, I’d like to work in industry. So far, my experience at UTMB has reinforced my initial resolve to work in industry and I have not considered pursing any further studies such as law or medicine. However, I would have like to participate in UTMB’s PhD/MBA program, but I never felt that I would have enough spare time to pursue and MBA while doing research. Overall, I have found my graduate experience at UTMB to be a rewarding one. I feel that I am receiving a well-rounded education with regards to coursework, hands-on research experience, and critical thinking. The fact that my graduate program requires me to give an annual seminar is providing me with important public speaking experience. The professional relationships that I have made here at UTMB will be invaluable during my scientific career. I am confident that I made the right decision by choosing UTMB for my graduate training.

I have had positive experiences at conferences. I am adequately prepared to interact and compete with graduate students from other institutions. I have applied for an NRSA, but have received priority scores just on the cusp of fundability. My mentor however, has been able to fund my research through her grants.

Personally, Galveston Island is a great place to live while going to graduate school. Galveston’s low cost of living helps to stretch the graduate stipend, and the relaxed atmosphere of island life helps me keep my perspective. Once a week I play pool in an amateur pool league which enables me to interact with people who are not associated with UTMB. As a result, I have a wide variety of friends in Galveston. I can’t image that there are many other places where graduate students can afford to live so close to the beach. There’s nothing more relaxing than walking my dog down to the beach for some exercise after a long day at the lab. I am extremely happy living in Galveston and attending UTMB.

Undergraduate institution: Fort Lewis College, Durango, CO
Age: 32
Gender: male
Nationality: American

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Michael S. Thomas

Why I wanted to enter graduate school? I have difficulty answering this seemingly innocent query succinctly; perhaps some understanding of my motivations to pursue a doctoral education may be gained through a retelling of how I came to attend graduate school. Shortly after completing high school, I enlisted in the United States Navy and began my training as a hospital corpsman. As a corpsman stationed with the Marine Corps I obtained patient histories, performed examinations, implemented care plans, and provided both preventative and emergency care while in the field. Our facilities were somewhat crude and physician support was rather limited making for a challenging and independent position that I enjoyed very much. However, after four years I elected not to reenlist and instead enrolled at a university with the goal of finishing my undergraduate degree as quickly as possible in order to return to my interrupted medical training at medical school.

Missing the fulfillment I enjoyed while working as a corpsman I very much wanted to continue working in some aspect of patient care. Fortunately, I found a full-time position as a mental health aide and was able to provide limited care for a special population of mentally retarded individuals who had also developed mental illnesses. It was my first exposure to the manifestations of psychiatric disorders and I attempted to learn all that I could about the diagnoses being made through both the patient records and scrutiny of available medical literature. Although my medical training was relatively limited in this new environment, I endeavored to learn all I could to be in a position to help those in my care learn to function more independently. Every day presented new challenges as any previous progress provided little insight into new difficulties with an individual who was in a constant struggle to find common ground with the rest of society. I was fascinated with how pharmacology helped to shape an individual’s reality and simultaneously disappointed with the limited knowledge of the mechanistic development of their disorders. My frustration arose from both the modest effects of neuropharmacologic treatments and my own inadequate attempts at helping them cope with their daily difficulties. This served to fuel my desire for medical training in earnest, but unexpectedly it also sparked an interest in research. I secured a position in a lab investigating the high incidence of neural tube defects prevalent in south Texas and the possible link to industrial pollutants in the environment. In the lab I began to learn the importance of critical thinking and sound experimental design in basic research, but it was my experiences in the clinical setting that drove my efforts to use basic research findings to advance clinical diagnostics and therapies. Realizing that I was most happy in a setting that combined both basic science research and patient care, I applied to the MD/PhD program. 

Unfortunately, I did not successfully apply to the combined degree program. Additionally, my grandfather passed on that year and these two events were to have a profound effect on the shaping of my future. It had been difficult watching my grandfather succumb to the devastating effects of Alzheimer’s, Although he had quit school in the sixth grade to work the family farm, Grandpa had always impressed me with both his intelligence and practical approach to solving problems. I felt compelled to be involved with research that might one day prevent deterioration like my grandfather had endured. Dissatisfied with my master’s thesis on developmental toxicology, I applied to and was accepted for a National Science Foundation grant to go to Japan and research mechanisms in Alzheimers etiology. My time working there was too short and I returned home completely committed to my course to begin my doctoral education in the neurosciences, with my goal of once again returning to my clinical education firmly fixed in my sight. I had presented the bulk of what was to become my master’s thesis at the Undergraduate Research Symposium the University of Texas Medical Branch at Galveston and had discussed my plans for the combined degree program with Jim Blankenship at a career day Texas A&M Corpus Christi. I had come to know some of the faculty at UTMB and had been very impressed with the passion of the faculty, including my soon-to-be-mentor Giulio Taglialatela, who impressed with me with his zeal for student presentations and direct manner in asking questions. After relaying the disappointing news of my failure to procure a position in a combined degree program, Dr Blankenship graciously offered me position as a graduate assistant in the Neurosciences department, provided I met all of the requirements. I had completed four interviews for the MD/PhD requirements at UTMB but they were geared for the dual degree program and not just graduate school and as such did not have a great deal of bearing for my impending graduate work. I had toured other campuses in Texas and met representative faculty during my medical school interviews but felt most strongly about UTMB so it was with great excitement and confidence in having chosen well that I accepted Dr Blankenship’s offer.

My graduate class was a hybrid of the old departmental curricula and the new BBSC program. We had all chosen a department before we were accepted by the graduate school. As such, each of my peers belonged to a specific department, each with its own requirements but we attended common core BBSC courses. This meant that I was to work with and get to know students from all departments, but due to Neuroscience Graduate Program (NGP) requirements, I also was introduced to the entire faculty in my department by meeting with individual faculty for one-hour presentations each day of the week. Additionally, I was given permission to immediately begin work in Kenneth Johnson’s lab researching a PCP animal model of schizophrenia while my peers focused solely on the BBSC Cell biology and Biochemistry courses. Working in a lab was profoundly rewarding, but it did detract from spending more time with my fellow students who had more time for study groups than had I and as a result I made fewer friends. I think this opportunity to build a peer support network is one of the greatest attributes of a common curriculum. As for the specific topics, I found myself thoroughly more impressed with the professors from different departments than I was of the subject material. For example, two professors who principally shaped how I came to think of scientific processes were in the department of Biochemistry and Molecular Biology. Wayne Bolen taught the first half of our biochemistry course and his passion for understanding the basis for biological reactions was contagious. Neil Howell gave both very specific lectures on mitochondrial respiration and the electron transport chain as well as very broad lectures on theories of maximum parsimony in molecular evolution. The contrast of these wide-ranging subjects was underscored by a relentless curiosity for the mechanisms of life. While other professors were teaching the minutia of such processes as prokaryotic transcription and translation as a body of facts to be assimilated and regurgitated upon examination I was spellbound by professors such as Drs. Howell and Bolen who used our knowledge of specific processes to build upon a larger understanding of the study of life. I was both intimately interested and profoundly disappointed in my BBSC experience and, interestingly, it had very little to do with the lecture material being taught. My reward came from seeing how we learn about a process as well as using what we have learned to gain a deeper understanding of life processes rather than expanding an ever larger and unwieldy body of facts. I think that this is what defines a broad based curriculum. It isn’t a superficial sampling of various disciplines as an all-you-can-eat buffet, but rather seeing how the scientific methodology fueled by a child-like curiosity binds us all as scientists regardless of specific endeavors.

Although we all had chosen a department before entering graduate school, specific departmental requirements were a favorite topic of conversation between classes and at various student gatherings. I feel that my departmental specific curriculum was appropriate given that I opted for additional coursework. Since my year, the additional coursework has been made mandatory, which I feel is appropriate. One advantage of the BBSC curriculum as stated above is the opportunity to meet very different minded students and form a peer network of students with very diverse interest, backgrounds and abilities. One advantage of departmental specific coursework is the opportunity to have numerous close-contact interactions with fantastic scientists and educators. Frequently my courses included many experiences with professors in a one-on-one or two-on-one settings making for a very rich and personal learning environment. It was very challenging working closely with such fine minds at such an early stage in my training and I found the experience very motivating.

As stated above, I began my rotations in my first semester of graduate coursework with Ken Johnson. I already knew that I wanted to work in the lab of Giulio Taglialatela, based on my previous experiences with him in the Undergraduate Research Symposium, the classroom (his lectures in the matters of intracellular signaling are always a favorite amongst students) and in personal meetings as part of NGP requirements, but chose to rotate in another lab that I found interesting for personal reasons. Dr. Johnson uses PCP administration in developing rodents as a model for understanding the mechanisms for the pathophysiology found in the brains of patients diagnosed with schizophrenia. Many of the patients I cared for during my undergraduate education were diagnosed with schizophrenia so I was very interested in studies in this field. Under Dr. Johnson’s mentorship I learned how to use in vitro models such as organotypic and dissociated primary cultures in a reductionist approach in understanding simplified hypotheses. This training was to prove to be very useful in my upcoming project in Dr. Taglialatela’s lab where I was to use many of these same approaches in my attempts to understand mechanisms for the selective neuronal degeneration found in the brains of patients diagnosed with Alzheimers disease. Dr. Johnson was very understanding and supportive of my decision not to join his lab and continues to be a reliable resource in the areas of neuropharmacology and in vitro models.

The conditions for admission into NGP candidacy were very similar to what my peers conveyed about their own departments. We were required to complete a take-home examination of approximately 10 questions followed by a successful presentation of our proposed work plan in an open forum and subsequent approval of our dissertation committee. The examination took approximately two weeks and when completed my answers were approximately seventy pages long. The questions were usually based on the findings in current primary literature and included formulating hypotheses, experiments and expected results based on the observations made in the assigned paper. This skill was reiterated in the proposal that was submitted in a NIH grant-style format. Upon successful completion of these requirements we were given more freedom in attending seminars and of course had no more assigned class work to interfere with our research. The timing of our candidacy requirements, especially the submission of our proposal in a grant-style format, was especially useful in seeking funding from outside the laboratory. Under the mentorship of my department head, Dr. Blankenship and my supervisor Dr. Taglialatela, I was able to receive four continuous years of funding including two years from the Sealy Center for Aging and the National Institute of Environmental Health Sciences.

Upon entering candidacy, it is easy to fall into an everyday routine and try to “do an experiment a day” as we are so often encouraged by our program director. We become part of a team learning to work with the departmental administrators in such tasks as ordering and publications. It also becomes important to attend and present research at national meetings. I have been to half a dozen national level meetings during my time in the lab and presented my research at all save my first. My first Society for Neuroscience meeting presented an opportunity to meet with our department chair hitherto I had only interacted with in a classroom setting. Bill Willis, our former department chair, generously funded my trip to New Orleans to attend the meeting even though I had not yet been in the lab long enough to submit an abstract. I have also learned to work as part of a research lab coordinating lab orders and maintenance duties with my lab mates. My work involves the use of animal models, to which I have written and currently update two animal protocols. As our lab was new at the time I joined I met with other established researchers in our department who were very helpful in enabling me to learn how to write a protocol that will be approved by IACUC. Safety is another very important issue when reporting to a lab. I currently serve as the Hazardous Communications Officer, which entails me introducing all incoming or rotating students to all of the specific hazardous materials used in our lab and educating them on the proper use, storage and disposal of these items. I also serve as the Lab Safety Officer and am responsible for maintaining and documenting safety procedures for all personnel working in the lab. While all these activities may seem mundane, they are necessary to the workings of a safe and productive lab environment.

My research has been adequately supported through the support of my mentor as well as both the previous and current department chair. Early on, I was provided with funds and equipment from various laboratories to assemble a stereotaxic surgical bench complete with gas anesthesia. The university provided exemplary training in the use of gas anesthetic on small rodents and Bill Willis once again generously lent me equipment from a departing professor’s lab as well as furnishing funds to replace equipment on loan from the anesthesiology department. My mentor has provided me with immediate feedback to all of my questions and has a real “open door” policy. I am very grateful for the support and guidance Dr. Taglialatela has provided me with over the course of my graduate training. I feel that he has always acted as my advocate and his candor is unquestionable. These personal traits are very important to me in a working relationship and even after five years of working closely with many fine faculty at UTMB I do not think I would choose any differently had I the opportunity to do so. His day-to-day rigor and nearly constant challenging encouragement have in no small way led to my successes in presenting my research. I have repeatedly won recognition at various local poster presentations both in and out of my department. I have received unsolicited praise from many of the faculty for my oral presentations, due to the time Dr. Taglialatela takes in preparing each of his students for their presentations and the questions that follow. Our weekly lab meetings are an important part of my training and everyone is expected to join in on spirited discussions of papers or recent data, including researchers very far removed from our specific research which is useful for looking at phenomena from varied points of view. This has been borne on a practical level in my committee meetings, which have proceeded very well.

Mine has not been perhaps the most typical graduate career. Foremost, I have the support of my wife, Anna, with whom I have been married for twelve years and we share in the joy of our ten-year old son, Scotty. My extracurricular activities have been somewhat limited but I have enjoyed the prospect of new challenges when they have arisen with the full support of my mentor. I have been elected to serve in the Graduate Student Organization both as a department representative and as the Vice-President. For two years I worked with a high school student, Kyle Stramblad, at my lab as part of the Bench-Top Mentoring Program. I have been part of a team taught Introductory Toxicology course at an undergraduate and master’s level here at UTMB and Texas A&M Galveston as well as part of a distance learning class at my alma mater Texas A&M Corpus Christi. Mary Moslen is the course director and has been instrumental in allowing me to have numerous teaching experiences providing critical support in helping me to learn to teach others effectively. I have been recently recognized for my teaching efforts and was awarded the inaugural Leon Bromberg Student Teaching Award. One of the most rewarding extracurricular activities I have been involved with has been as serving as Senior Co-Director for the National Student Research Foundation which hosts a national level scientific meeting for medical and graduate students from across the country. Being responsible for planning and executing an event of such magnitude has been one of the greatest challenges I have ever been able to meet. This was a profound lesson in the need to work with a group in order to get the best job accomplished. This group not only included other co-directors, but senior administrative faculty such as the Dean of the Graduate School, Carey Cooper and the Dean of Medicine, Stan Lemon and their respective staff as well as the entire Faculty of Medicine.

It has been a very rewarding experience but I feel the absence of patient care intensely. It is now the summer of my fifth year as a graduate student and it does not seem so long ago that I decided to leave the military to begin my academic training in pursuit of my ultimate goal of providing patient care as a physician. I have no regrets about completing a graduate degree and feel that my experiences at UTMB have been as personally rewarding as anywhere in the world. Of course, I have ideas for specific changes that I feel would improve the graduate education but I have no doubt that I am in the company of a great number of dedicated faculty who feel just as I. My thanks goes out to faculty such as John Papaconstantinou and Billy Phillips who have chosen to use their awards to better improve graduate education in such endeavors as this essay and the setting up of the very first student teaching award here at UTMB. There have been a few surprises and more than a few challenges along the way, but I, with the support of my wife and son, feel the sacrifices we have made are acceptable given my determination to have a career that enables me to pursue my passions for both medicine and research.

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