PROSPECTIVE STUDENTS
Changing Demands in Research: Student Perspectives at UTMB
How these essays came to be…

Basic Biomedical Science Curriculum

My interest in graduate school began while taking a general microbiology course during my junior year of college at Stephen F. Austin State University. As the semester progressed, I found myself increasingly fascinated with this particular field, especially in the areas of environmental and clinical microbiology. My initial involvement in research began while carrying out an undergraduate project involving the process of bioremediation (detoxification of contaminated soil through stimulation of endogenous flora) during my senior year. Upon completion of my Bachelor of Science degree, I pursued a Masters degree continuing my work in environmental microbiology. I used this time to decide if I wanted to seriously pursue a career in research and eventually decided to proceed on this course. My decision was to continue in the field of microbiology, but my growing interest in infectious disease research impacted my decision to pursue a Ph.D. in clinical microbiology.

I wanted to attend an institution that allowed me to remain in Texas and relatively close to my family and friends. I also felt that there were plenty of reputable schools within the state in which to seek my degree. To increase my chances of admission, I applied to every state institution offering a doctoral degree in microbiology. I was granted interviews to several schools which included Texas A&M, University of Texas Medical Branch, Baylor College of Medicine, and University of Texas Health Science Center in Houston. After interviewing at various schools and receiving several letters of acceptance, I decided to pursue my Ph.D. at The University of Texas Medical Branch. There are several reasons why I made this choice. First of all, I was currently working as a research assistant in a cancer research lab at UTMB and thus I already had some insight into what the school and graduate program had to offer. I had also concluded that UTMB had a much more diverse faculty which could provide a wider selection of research interests in comparison to other institutions at which I had interviewed. This was one of the critical factors on which I based my decision. I had not yet decided on a particular area to pursue my research, and, therefore, I wanted the flexibility of attending an institution which provided me with the most options. Other factors included competitive stipends, location, and cost of living. The UTMB Graduate Program offered competitive funding and Galveston seemed to be most reasonable choice when addressing the other factors.

The interview process at UTMB and the other institutions was very similar regarding the interviews and activity schedule. This mainly included a full day of back-to-back interviews, meals with different students and faculty, and touring the local area with nightly activities. Some institutions presented a more sociable and relaxed atmosphere, while others appeared were less personable and exhibited almost a business-like environment. The latter was definitely a concern when considering that I would be working in this environment for several years. I found UTMB to be an intermediate between these two settings and that was the work environment that I found most appealing. I found myself to be in a unique situation during some of my interviews. Some of the schools sent me letters of acceptance prior to being interviewing. I must admit that the stress of the interview process was relieved to a great degree when interviewing with these schools which contrasted the traditional interview process. I found my experience to be more of one in which I was evaluating the schools to make my decision on which to attend as opposed to which schools would admit me into their program. My interview with UTMB gave me an overall idea of what to expect during my first year of graduate school, but no one could really provide insight into the highs and lows of what I would be going through my first year of the program.

My experiences with the integrated first-year curriculum were both positive in some respects and negative in others. I liked the option of having the freedom of not being forced to choose a department during my first year of graduate school. The three core classes (Cell Biology, Biochemistry, and Molecular Genetics) were set up such that different lectures were taught by different faculty members who specialize in that subject area. The major flaw I found with this arrangement was that not all faculty members were effective lecturers, and, thus, there would be both productive and non-productive lectures based on the individual lecturing styles of the speakers. This became a problem when preparing for exams because questions based on lectures taught by the less effective speakers placed me and my classmates at a disadvantage in studying that material. This was due to the fact that the material was not presented clearly and in an understandable manner thus resulting with misinterpreted information or material which was not understood at all. The core classes did, however, provide a nice foundation of material from which I and my peers could expand upon as we began taking our departmental classes. Another problem with the first-year curriculum was the length and number of required course electives. These eight-week courses were too brief to gain any depth of information from each class. In addition, a number of these electives were required during the first year of school which made me feel that the curriculum was substituting quality for quantity in terms of these electives.

To pursue my studies in infectious diseases, I decided to join the Microbiology and Immunology Department upon entering my second year of the graduate program. The criteria I used to base this decision included choosing a department that would provide me with a strong foundation of basic and traditional course work from which I could further extend my knowledge of infectious diseases and their causative agents. With this department, I felt confident that I could find that foundation through the required departmental courses (Pathogenic Bacteriology, Virology, and Advanced Immunology). I also felt very comfortable interacting with the departmental faculty and staff, which is an element I didn’t experience with other departments.

When choosing my laboratory rotations, I attempted to select diverse labs focusing on different pathogens and carrying out work on different aspects of each microorganism. These rotations included working in labs carrying out research in the fields of bacteriology and virology, each focusing on different areas, such as molecular signaling mechanisms, pathogenesis, surface protein characteristics, therapeutic treatments, and genetics. I believe that choosing a lab is one of the most significant decisions to make as a graduate student. Two major factors which can impact an individual’s progress and overall experience as a student include the working environment of the lab and the relationship established with the primary investigator. When considering these factors, I felt that additional rotations were a wise investment during my search for a lab and pursued three rotations beyond the traditional three required for my program.

I was also looking for a mentor who would be supportive of my progress as a student in their lab and one who would not treat me as just another technician. On a personal level, I wanted a mentor to be someone who would allow me the freedom to do my work at my own pace in their lab to meet my personal deadlines. I also wanted a mentor who would make time in their schedule for personal meetings so I could receive suggestions and feedback regarding the progress of my work and interpretation of my experimental data. As I progressed through my rotations it became increasingly clear that I was interested in the field of bacteriology and I was fortunate to find a mentor and a lab that I felt comfortable joining and which satisfied most of the attributes I was looking for. While my interactions with other researchers during my rotations were very positive experiences, those labs did not satisfy my expectations for the environment in which to work for the duration of my graduate studies. In the event that I would have been forced to choose between a laboratory which conducted research focused specifically on my scientific interest or a lab which provided a positive and productive work environment, I would have chosen the latter. I feel that your work environment can have a major impact on your attitude towards your research and productivity in the lab. When looking at the process of graduate school as a whole, this is only a temporary compromise until graduation after which you can pursue your own particular research interests for the remainder of your career.

The most miserable and yet fulfilling experience that I have experienced as a graduate student has been the dreaded qualifying exam. This exam has been a major decisive factor for the direction my own career as well as my fellow graduate students. I have witnessed my peers both successfully excel through this “trial by fire” and continue in their graduate programs while others were dismissed from their respective departments or chose to leave of their own accord. It eventually becomes a decision of what one is willing to sacrifice to acquire their doctoral degree. In my case, I had already sacrificed enough of my time and money to complete the first half of my graduate studies. I had already survived the onslaught of first year classes and departmental classes, and I was determined to graduate. I spent several months writing my proposal and preparing for my oral examination. For those who have never taken this exam, it is quite difficult to decide how to prepare for it due to the variability among committee members for each student and different departmental requirements. I felt that I prepared as thoroughly as I could and was overwhelmed with the amount of information I attempted to learn both from my classes and the scientific literature on which my proposal was based. As I presented my proposal to my committee I started to have difficulty in defending certain aspects of my experiment designs which I proposed in my aims sections. The questions seemed to increase and I started to feel my confidence decline further and further. It is at this particular point that one’s committee members start to “smell blood and then go in for the kill”. It was not that I felt my committee members were unfair in their evaluations and final decision, but, regardless, the final judgment was not in my favor. It is at this point I felt like someone had just dropped a car on my head. I was devastated, angry, sad, and extremely disappointed. After a few days of reflection, I looked at my options which were: one, to re-evaluate my career choice or two, to re-take the exam in a year (this was standard procedure for my department). After much thought, I decided to pursue option two. Much to my excitement and joy, the results of my second examination were the exact opposite of the first. Not only was my committee pleased with my performance in contrast to my first examination, I was ecstatic by the compliments from different committee members with respect to my overall presentation. This made my decision to retake the exam well worth the wait. What I took away from this experience is that one should never give up own their career goals, but to remain focused and persistent until they finally reach that goal.

Since the qualifying exam, I have gained a renewed determination to push forward with my research and graduate with my doctoral degree. I am currently in the process of applying for candidacy and forming the supervisory committee for my dissertation project. I maintain positive relationships with my fellow students, departmental faculty, and staff. All of these individuals can be very helpful on many levels--whether it be advice on a particular experiment or help in making handouts for a presentation. I feel I have a good relationship with my mentor. He is very supportive of my work and growth as a student. I’m given the freedom to carry out my research at my discretion and seek independent support and guidance from other faculty members. I am satisfied with my lab and the availability of equipment that I use to carry out my research. Moreover, in the event my lab does not have what I need to perform a task, I can always seek assistance and equipment from neighboring labs which is a nice alternative. At this point in my graduate career, I have no regrets about the lab and mentor I have chosen. After almost two years of research and being awarded external fellowships, I feel that if I had to change mentors it would be at a great disadvantage to me, considering the amount of research I have completed and the time I have invested in my work. I feel that the guidance I have received from my mentor thus far has been very valuable, and the continued support I receive from other faculty members has had a major impact as I continue through the second half of my graduate career. I’ve had limited interactions with the Dean’s office and the graduate school administration, but those few interactions have been very positive and efficient when support was requested.

My experiences, thus far, from the graduate program have definitely confirmed my decision to further pursue clinical research in the academic or private sectors. I am even considering pursuing an M.B.A. to become more competitive for potential jobs if I do decide to look into business-related areas such as biotechnology. However, my future direction has not yet been formulated. I’m keeping my options open to see what opportunities become available as I approach graduation. My present career objectives remain consistent with my goals from beginning the graduate program at UTMB. Two major contributing factors which have helped me stay on track continue to be the support I have received from my mentor, peers, and departmental faculty, and the encouragement given to me by my qualifying exam committee after completing my second qualifying examination. In addition, my determination and persistence have helped me to continue my journey through the graduate program until I acquire my degree. After graduation, I look forward to continuing my career as a scientist and contributing to my respective scientific area of interest.

|| GSBS Home || Return to Table of Contents || Back To Top ||

About myself

My name is Mohammad Eghtedari; my twin sister and I were born in 1972 in Shiraz, Iran. I completed elementary, middle, and high school in my hometown. During high school, I especially enjoyed my physics courses and in 1989 was invited to join the Iranian national physics team which would attend the world-wide Olympiad of physics. I got my high school diploma in mathematics and physics in 1990 and my M.D. degree in 1997 from Shiraz University of Medical Sciences.

Although I was a physician, I enjoyed basic sciences more than my clinical experiences and this is the main reason why I am pursuing a Ph.D. here at UTMB instead of practicing medicine. My extracurricular activities include designing and making electronic circuits and model aircrafts, as well as computer hardware and programming.

Last summer, I married a lovely girl who had recently graduated from UTMB and is a pediatrician. Currently, I am a third year graduate student at the Center for Biomedical Engineering and am preparing to propose the title of my thesis very soon.

Applying to graduate school

I decided to become a researcher in biomedical engineering a long time ago. Early on in medical school, I realized that being a clinician was not what I wanted and so I started asking my professors about possibilities for pursuing research. When I explained my interests and capabilities, they advised me to apply for biomedical engineering; a field which they believed was a promising discipline and matched my interests. Because of that, I planned early in medical school to improve my knowledge in mathematics, physics, computer sciences, and electronics while I was studying medicine. It is noteworthy to mention that the title of my thesis in medical school was “Designing and making a pulse-oximeter” which won the letter of excellence at that time.

At the time I graduated from medical school, there were only two biomedical engineering departments in Iran. Both of them were a branch of electrical engineering and so chose prospective students with engineering, rather than medical backgrounds; thus, there was no way for me to study biomedical engineering in Iran. This made me seek opportunities abroad. Searching the internet, I found many opportunities in the US for a medical doctor to study biomedical engineering, and among them, the program at UT Austin appealed to me the most.

Taking the GRE and TOEFL was a general requirement for applying to graduate school but due to the conflicts between the U.S. and Iran, there was no center in Iran to take these tests. I remember my frustration while trying to order reading materials for these tests online. As soon as I would enter Iran in the shipping address, a message appeared on the screen explaining that due to the U.S. sanctions, they cannot send any books to Iran and so my order was canceled. This made me sad for a while but I recovered soon and searched for alternate opportunities. I started reading very old books that I found in a shop to prepare for TOEFL and GRE and traveled to the United Arab Emirates (U.A.E.), a small country located south of Iran, in order to take these tests.

Having GRE and TOEFL scores in my hand, I applied to U.T. Austin for a Ph.D. in biomedical engineering. They were quite interested in my file after interviewing me over the phone, but because of the fact that I was not an engineer, they could not accept me in their program. However, they advised me to apply to UTMB which was accepting students who had a biology background. They recommended me to Dr. Motamedi, who is my current supervisor at UTMB, and he kindly promised to support my application after he reviewed my file and talked to me over the phone. His major concern was that many of the medical graduates from the Middle East who come to the U.S. as a Ph.D. student leave the laboratory and continue their medical educations as a resident before finishing their research project. Fortunately, I convinced him that I am not that kind of student.

During spring 2001, the committee members at GSBS reviewed applicants to select students for the following fall. I could not wait to hear from the committee through mail and so I was calling their secretary every week to get the updated news. Finally, the secretary told me that the committee who reviewed my file in their last session did not make any decision; “This may be good or bad news for you; call us next week” she added. That week was one of the longest weeks I have ever had in my life. The following Friday, I was able to clearly hear my heart beat at 7PM when I was dialing their number from Iran… Beep… it was about 10:30AM Galveston time… Beep…

The lady answered the phone and recognized me because of my foreign accent…”Yes Mohammad, I am writing you an e-mail … congratulations, you were granted…” I don’t remember if I said goodbye to her or not as I was so excited that I could not talk … All of the efforts and time that I spent over the years had paid off; my dreams were changing into reality; it was a very delightful feeling. I hung up the phone and cleared the tears from my eyes.

What happened between spring 2001 and fall 2002

As soon as the excitement of receiving the letter of acceptance cooled down, I started to apply for a student VISA. Again the problem was that there was no U.S. embassy in Iran and I had to travel abroad to get a VISA. Although it was more costly, I decided to apply at the US embassy in Ankara, Turkey instead of the U.A.E. The interview was short and easy and they accepted my documents but they told me that because of my nationality, I would have to wait until they get my security clearance from Washington. The security check normally takes 4-6 weeks, they added.

After the interview, I went back to Iran happily and waited for 4 weeks; then I called them weekly but my VISA was not ready even after 8 weeks. It was very stressful for me to see that I had been accepted at UTMB and the deadlines for fall registration were close, but my VISA was not ready. So, I packed and said goodbye to my family and friends and went to Turkey to stay at a hotel close to the embassy in order to get the VISA the very next day after my security becomes clear. I stayed there for another four weeks but my VISA was not ready…

It was in the afternoon and I was watching C.N.N at my room in Elite hotel in Ankara when that horrible attack of 9/11 occurred. “What is going on?”, I asked myself. I was shocked. When the twin towers collapsed, I felt like my dreams to study biomedical engineering were collapsing… The U.S. embassy was closed… No chance to get VISA… I was certainly a victim of the attack of 9/11, on a different level.

I returned to Iran very disappointed. Everybody was asking me of my situation and I did not know how to respond. After a while, I decided not to ruin my future by waiting for a U.S. VISA anymore and applied for similar positions in Europe. The application process to European institutions was much easier than that of US. By February of 2002, I was at Aarhus University (Aarhus, Denmark) to study for a Ph.D. in cell physiology. I was quite happy with my position over there, but could not forget my dreams about biomedical engineering.

Three months after starting a Ph.D. program at Aarhus University, I received an e-mail from the U.S. embassy informing me that my VISA was ready. Now I had two choices: to stay at Aarhus University and become a cell physiologist or to come to Galveston to become a biomedical engineer. Because of my longstanding dreams, I decided to quit Aarhus University and come to the U.S. to study biomedical engineering.

Thanks to the cooperation of the GSBS and the department of cell physiology and biophysics for issuing a new I-20, I was able to register for the BBSC in the Fall of 2002.

The First year at graduate school

I came to Galveston in May 2002 and started to take research rotations until August when I joined new students to register for the BBSC program in fall 2002. I already had an M.D. degree and had passed a cell biology course; thus I decided to take the place-out examination to test my knowledge in this field. I was fortunate to be the only student in my class who passed that exam and so dropped my cell biology course that year. That success made me feel happy especially when I saw the response of the faculty members at the cell biology program when I met them in one of the welcome parties. By dropping the cell biology course, biochemistry was my main course work during fall 2002.

The biochemistry course was very exciting to me because it started with thermodynamics and energy conversions; the topics that I remembered well from medical school. I also liked the way Dr Thompson presented his lectures. I was sitting in the first row of the auditorium all the time. His open-book exam was also one of the best exams I have ever taken; however, I made minor mistakes in that exam by going into unimportant details and making the questions more complex.

During the Fall semester, we had small group discussions every week as part of the biochemistry course. I liked these sessions because there was a chance for me to discuss topics that were presented that week. However, sometimes the facilitators did not know the answer to our questions -which was not a shame at all- but were trying to escape it by asking another question. This made me nervous a few times. I believe “I don’t know” is the best answer when we do not know the answer!!! It happened three or four times that after discussing the questions with the instructor, I got different answers from what I got from facilitators. Thus, I believe it is very important to choose a facilitator for small group discussions who has enough experience in that field.

The other part of the biochemistry course was about nucleic acids which was less interesting to me than the first part; however, I continued following the lectures carefully and reading all the required materials.

The worst parts of this course were the topics on enzyme kinetics. The way the instructor presented the speed of reactions was totally different from what I had learned in medical school. I was confused and it was very hard for me to understand the new materials. It was amazing for me to hear from other students that they had similar feelings but they simply preferred to memorize the materials rather than understand them. At first, I thought I could not do that and I had to find a way to understand them, but I became disappointed very soon when I got no response to my questions from the instructor by e-mail. After the third time that he did not reply to my email, I stopped asking questions and memorized the materials just to pass the exam. The exam of the last part of the course was also strange; we had three to four hours to answer questions and even this was not enough for many of us to finish it!!! There was something wrong with that exam.

Despite my initial interests and the efforts I put into biochemistry, my final score was a B. I was deeply sad and believed that I did not deserve it.

Our main course in spring semester was genetics. I was not interested in this course and hesitated to sit in the front row as I used to do in biochemistry. The score of B in biochemistry made me mute during the genetics course. I did not ask any questions during lectures, nor did I participate in the discussions in small groups, unless I was asked. Because I did not actively participate in discussions, I hardly remember the materials I memorized at that time. Talking to other students, I found that an easy way to pass the exam was to find and memorize the answers to the questions of the exam in previous years, as the questions did not change. I didn’t know it until I saw other students memorizing them. Although this method of studying was not right, I decided to employ it for genetics. Surprisingly, at the end of the genetic course I was granted an A. It was very strange for me to see that several questions in the exams were copied from that in last year. If we assume that the main goals for taking an exam at the end of courses are to encourage students to study the materials and also to evaluate them based on their knowledge, then none of these goals can be achieved by repeating questions verbatim from prior exams.

First year graduate students are supposed to do research rotations in at least three laboratories in order to become familiar with different research projects before joining any of them permanently. Despite the fact that I knew from the beginning which laboratory I was going to attend, I had to take two additional laboratory rotations during my first year.

My first rotation was very productive, as I learned many techniques that are used in cell biology, but I had never used before. My second rotation, however, was different because of a fourth-year graduate student in that lab who wanted to tell me what to do. To be honest, I did not like it when I noticed that he was even keeping track of my arrival time in the lab. But very soon, I impressed him with my interests and sincerity and so we became good friends and I learned a lot from him during that rotation.

After completing these rotations, I came back to my original laboratory to take the third mandatory rotation and comply with the regulations. I made a rule for myself at that time to do my best to show everybody that I am very eager to learn and am not afraid of working hard. This is the key to having a friendly relationship with other staff in the lab.

I like my current research project because it is all about what I love to learn; in addition, my supervisor allowed me to actively participate in that project from the very beginning stages of writing the grant proposal to designing and conducting the experiments to the stage of reporting the results. The other thing that I like about my current job is that we are working in a unique group of scientists from different countries; i.e. Russia, Germany, China, Mongolia, Iran, and Belarus. My supervisor is so kind to me that sometimes I feel like he is my big brother rather than my supervisor.

Taking the qualifying exam

During the second year, students are supposed to pass a qualifying exam which is designed by a committee inside each department. Regardless of its form, taking an exam is stressful for any student and the qualifying exam is not an exception. Being over 30 years old I have lost my capability to memorize material but have earned the knowledge and skills required to analyze them. Thank God, the qualifying exam was in the form of a take home exam in our department. However, the regulations for the qualifying exam were changed recently and I was the first student who was taking it under the new regulations. The committee gave me a hypothesis and a one-week deadline to design an experiment to test that hypothesis and write a 10 page grant proposal. Additionally, I was supposed to present and defend those answers in front of the committee members the next week.

After receiving the question by e-mail, I carefully read it several times and then started to think and search the literature to learn more about that subject. I guess one of the most important strategies in such a situation is not to jump in to writing until you have a clear understanding of both the question and your proposed answer. Thus, I continued reading and thinking until the very last night when I started to write down my ideas. I was working that night until 6AM the next morning!!

The verbal part of the exam was much more stressful to me than the written part. Although I started my presentation quite calm, the condition changed when committee members started to ask me questions that were hardly related to my written part. I became nervous but attempted to answer them to the best of my knowledge. At the end, I was worried about my performance in the exam. They sent me out of the room to discuss my final score; after ten minutes, my supervisor called me in and congratulated me for passing the exam with an overall score of 97%.

I heard from my supervisor that because of my nervousness at the end of the exam, I was interrupting people to answer their question before they finished their sentence; he advised me to be more patient next time and listen to their question through to the end before starting to answer it.

Plans for the future

It may be too ambitious for a graduate student to finish his Ph.D. program in less than four years, but I will work hard to do that. My supervisor and I believe that combining my knowledge in medicine with that of basic science, which I will achieve during my studies as a graduate student, will enable me to conduct multi-disciplinary research in future. Because of that, I will probably apply for a post-doctoral position in molecular imaging, which is my field of interest, as soon as I finish my current Ph.D. program. Having both publications and Post-doctoral experience will strengthen my resume to get an academic position in the future.

Third year graduate student
Center for Biomedical Engineering

The University of Texas Medical Branch

|| GSBS Home || Return to Table of Contents || Back To Top ||

My initial interest in applying and attending graduate school began with my desire to further my understanding of biological processes. For my undergraduate education, I attended a small liberal arts university allowing me the opportunity to establish a firm foundation in biology. My investigation into the career opportunities of science revealed to me I could take one of two roads. I could attend medical school and take the road more traveled at my university or I could try a new less traveled road represented by graduate school. I chose graduate school because it offered me a challenge and an opportunity to pursue my overall interest of understanding and further characterizing the underpinnings of human physiology and pathophysiology. My initial choice to study pharmacology was fostered by my undergraduate mentor who gave me invaluable information on how to apply and choose a graduate school. Upon choosing to attend graduate school, I decided to pursue a Ph.D. instead of a Masters Degree with the goal to become an independent researcher in charge of my own laboratory.

When applying to graduate school I applied to multiple schools in Texas based on my general interest of pharmacology. My final decision to attend UTMB was based on my interview with the faculty in the Department of Pharmacology and Toxicology and the GSBS. One of my deciding factors was that the BBSC gave students the freedom to choose their department and mentor after they had experienced the laboratories during rotations. Another key factor in my decision was the open door policy that many of the faculty in pharmacology presented to me on my interview. I was naïve of the research environment, so the openness and friendliness of the faculty was important in my decision to attend UTMB and future success at UTMB. The interview process at UTMB was similar to other schools that I applied to in that it involved interactions both with students and faculty. I believe the interview process was helpful in not only allowing the faculty to evaluate my qualifications and learn my interests but also allowed me the opportunity to determine which faculty’s laboratories I should pursue further and which ones I should avoid. Additional beneficial part of the interview process was the numerous interactions with current graduate students. These interactions at meals and in small groups allowed me to gather information pertinent to the educational pro and cons of UTMB and general information on life in Galveston. One main difference between my interview at UTMB and the other schools I applied to is that at the time of my visit to UTMB I had not been previously accepted. My visit to UTMB was the last of the schools I interviewed at so after weighing the pros and cons I decided on UTMB. After receiving the acceptance letter from UTMB I experienced a sense of elation and relief that the process had been successful.

When I arrived to UTMB and started my classes I was fearful of the difficulty of the curriculum. My initial anxiety resided after taking my first couple of tests. The first year curriculum allowed me to expand on the knowledge I obtained from my undergraduate education. The team teaching approach gave me the opportunity to learn from experts of the field and be introduced to new faculty and the focus of their laboratories. One positive was that the courses focused on learning the basic principles instead of focusing too much on the details. This knowledge of basic biological principles helped me with my 2nd year pharmacology classes and the design and execution of my research project. The only major disappointment I experienced with the 1st year coursework was the BBSC modules. In my year the modules were in their early state of development so the breadth and depth of the modules were lacking in some cases. I know these have since been changed showing that UTMB is willing to listen and adapt the coursework to meet the needs of the students.

I chose the Department of Pharmacology based on expertise of the department in my two interests of drug discovery/characterization and the central nervous system. However, I found that the departmental curriculum was too condensed. Pharmacology provides a vast, intricate, and difficult field of study. The field requires students to learn human physiology in combination with how the drugs work on the different systems and disease states of the human body. This means students miss out on the proper breadth and depth necessary to adequately understand the field of pharmacology due to the condensed nature of the courses. Once again, the input of the students was taken into account and appropriate changes have been made to better the curriculum.

My choice for my first rotation was based on my interest in neuropharmacology. When I came to UTMB I had only a small amount of previous experience. After an initial talk with my current mentor, I felt he would provide me with the training and support that I would need in my first extensive laboratory experiences. Following my first rotation, I had decided that I would stay in the laboratory. Based on this I designed my second rotation to learn advanced techniques to use on my research project. I believe being upfront with the professors you are doing rotations with is essential. I originally planned to do three rotations but decided to remain in my second rotation for an extra eight weeks. The person I was going to do my third rotation with was very understanding and preferred I stayed in laboratory where I could gain the most information.

In the Department of Pharmacology and Toxicology the qualifying examinations are administered in the spring of the 2nd year. Upon completion of my qualifying exams, my mentor encouraged me to apply for a predoctoral fellowship from NIH to acquire my own source of funding. The application date for the grant fell in December so I set up my proposal to coincide with the grant due date. I feel this approach allowed me to gain invaluable experience in grant writing. Following my admittance to candidacy I felt a load off my shoulders. This event marked my transition to be fully devoted to my research project, which is a significant accomplishment in the career of graduate students.

Currently I have begun my fourth year of graduate school and have been admitted to candidacy for almost one year. My experiences in the Department of Pharmacology and Toxicology have been positive. The faculty in Department of Pharmacology and Toxicology are all willing to help in any way they can. The faculty in the department provides students not only help with required coursework but with other invaluable skills such as grant writing and critiquing papers. I have realized help and advice comes from new assistant professors up to the chairman. The chairman of the department is very student oriented and very concerned with the success and proper progression of graduate students through their graduate careers. This concern can be found through all positions and levels in the department. The support staff of the department provides an important resource for graduate students. I have found the administrative staff to be key players in helping with the small things that sometimes go overlooked in the everyday life of a graduate student. For instance, the administrative staff supplies help with tasks like scheduling, travel, and grant submission. Although these tasks may be overlooked they are key to the success of most graduate students and should be utilized as much as possible.

I had very limited experience in the laboratory before entering my first laboratory rotation at UTMB. I chose my mentor based on his willingness to sit down and walk me through the early learning process necessary to become a productive laboratory member. My mentor was a relatively new when I came to UTMB so he still spent a good amount of time in the laboratory. His presence in the laboratory afforded me the valuable hands on teaching necessary for learning a rather challenging technique. Without his tutelage I feel I would have struggled in my initial introduction to bench science. This approach to learning the in and outs of the laboratory allowed me the opportunity to gradually progress into understanding how to become an independent researcher. I believe the hallmark of a graduate education is the ability to become an independent thinker and researcher. In order to progress into an independent scientist it is important for graduate students to take away as many skills as they can while they are in graduate school. I try to seek out every possibility available to enhance my knowledge of my chosen field and tips for becoming a better scientist. Along with my mentor my committee members have been crucial in guiding my scientific career at UTMB. The committee members play a pivotal role by providing an extra voice in your graduate school education. My committee has given me key advice on the design and execution of my dissertation project. The members of the committee are an excellent resource and probably are underused. Overall, my experience to this point in my laboratory has been uniformly positive. The guidance I have received so far I feel has provided me with the skills necessary to succeed as an independent researcher.

Outside of the department and laboratory I made many key contacts with other faculty and students. My faculty contacts outside of our laboratory supplied me with techniques previously unavailable in our laboratory. I found collaborations both inside and outside our laboratory to be very rewarding. Through collaborations, I was able to obtain three publications that would not have been possible without making these key contacts. I would strongly encourage students to pursue as many contacts and collaborations as they can during their stay at UTMB. These contacts facilitate the process of finding a job and future networking at scientific meetings. I have attended scientific meetings annually which are instrumental in the development of my career. The scientific meetings afford me the chance to investigate new ideas in the field and network with researchers in my field.

My experiences during my time at UTMB have supplied me the skills to succeed as an independent researcher. My original plans upon entering UTMB were to pursue a career in industry performing pharmaceutical research. I have changed my plans now to include a career in the clinical arena. I now would prefer to pursue a career involving hands on experience with patients utilizing the information gained from the bench and applying it to clinical research. I am still not completely decided on my exact future plans. Options I plan to explore include obtaining further education in a medical related field and/or pursuing a job working in clinical trials.

If I could go back and change my decisions coming out college I would still happily make the same decision to attend graduate school. Even though there are many peaks and valleys with science, the peaks outweigh the valleys. I believe the skills and information I have obtained at UTMB will play a pivotal role in my future. Graduate level education has given me the ability to think and work more independently while still playing a leadership role. In addition, it has supplied me with communication and thought process skills that are applicable in most aspects of life.

James Sanders
Tarleton State University
25 years old
Male

|| GSBS Home || Return to Table of Contents || Back To Top ||

As I am sure has been the motivation for many who have entered the field, science has always seemed to come naturally to me. I’ve coasted through class work and major concepts because things simply made sense. Fortunately my “que sera sera” attitude has served me well in my choices of career and education. Declaring that my major was biochemistry as an undergraduate was the easy part, stating vague intentions to enter medical school was due to my own naiveté. Threats of disownment from my mother and the realization that medical doctors are merely diagnosticians, not people who fashion cures for illness, helped me to realize that the wonderful academic environment that I was immersed in was created by people with PhDs.

The instinctual approach to science that I mentioned earlier made me skip over the template for drawing the possible conformations of a molecule and its accompanying energy diagram on my first Organic chemistry exam, and although I completed the problem, I did so backwards. I also received zero points from the TA. The professor was impressed and amused when I approached him, and from that point on I was lucky enough to have stumbled across an undergraduate mentor. He encouraged me to apply and accept a position conducting research during the summer of my second year. He also gave me a great deal of freedom in designing labs and tinkering with analytical equipment as I progressed into my third and fourth years. Having worked in industry and academia himself, he helped me find the scientific path that fit me. Following the completion of my bachelors’ degree I spent a disastrous two months working at a private environmental analysis firm, and a pleasant year teaching in a local high school. All to find that I didn’t want to do any of these things when I grew up. I had already decided that I needed an advanced degree in the sciences, but industry wasn’t for me, I wanted to find new things simply because I found them interesting. Likewise academia did not inspire me as it would require me to divide my time between teaching, administrating, and researching; all of which I would want to do to the absolute best of my ability, and in my mind would necessitate near exclusivity. While I toyed with the idea of a masters, I let application deadlines pass me by and decided that the intermediate wouldn’t get me to the point that I would have some independence in my research, not to mention that I would be paying my own way. Although the doctoral stipend is modest, it is manageable, and much preferable to no income at all.

So I started applying to graduate schools for a doctorate. UTMB was one of the universities that sent me information based on the release of GRE scores. I pulled it back out of the pile when I started looking for places that were doing research in gene therapy and my computer searches had revealed that it could be found down here. I applied to UTMB, the University of Colorado, and the University of Pennsylvania. In the meantime, Jesse Gelsinger had died during a gene therapy trial at UPenn, and was firmly scratched off the list. I knew enough to realize that their funding would be a mess for years to come. UTMB was my first and friendliest interview. Not only was I flown down first class, but I also had a room to myself in an exquisite hotel. It would have been shallow to decide to attend UTMB based on accommodations, but it was the sentiment that went behind the extra effort, and the kindness that everyone showed while I was here that didn’t appear to be rehearsed, but inherent. I was sure that I was making the right choice when I was called by a professor in the department that I was most interested in, who informed me of my acceptance, before ever having received a letter.

There are some things that I regret not being told during the interview process because they made it difficult for me to find a lab to call home. While I was interviewing I had wanted to meet with Drs. Brian Davis and David Brown, both of whom were doing research on gene therapy. Rather than listening to a current student who told me that he originally had wanted to do gene therapy, but couldn’t find it here, I let the professors reassure me that Drs. Davis and Brown had scheduling conflicts. In actuality, neither of them was accepting graduate students, but were building their own companies, and were on the brink of leaving UTMB. Suffice it to say that I couldn’t imagine being happier in another lab, but my rotations forced me to accept that gene therapy was simply a technique, and might not be available as a research project here at UTMB.

What really sold me on the school though was the integrated first year curriculum. Although I had a strong background in biochemistry, I expected that graduate school coursework would be rigorous and demanding, and felt that I might need some leveling out time that the BBSC at UTMB looked to be able to provide. I was also leery of making a decision about a department sight unseen. I secretly feared being stuck in a place where you never saw more than the five or so faces of the other students pursuing degrees in similar topics and that the department might encourage the locking of graduate students in the lab closet. While I am still happy with my first year of classes I am disappointed in the depth and breadth of the knowledge base. There were minor details, such as the names of certain signaling molecules and polymerases, but all in all no major additions to the information I had gained in college. I found that the most challenging portion of the coursework dealt with deadlines and time management, not content. And rather than providing highly specific information, the modules fell short due to time constraints, poor organization, overlapping material, and limited topic selections. I can see how it is impossible to please everyone and the course design was a necessity considering the diverse background of the incoming students. The range of experiences that my classmates brought with them was a bonus, but the watered down science was a disappointment. I almost wish that it were possible to target those students who may face problems, due to limited exposure to the advanced sciences, and require them to arrive a month earlier for an intensive workshop whose purpose was to bring them up to speed.

On the matter of selecting a department Dr. Blankenship set my mind at ease. Addressing a gathering of the first year students he had said that “if you want a particular kind of research here, you can find it in any department, or we’ll put it there for you”. He also said that choosing your department was often a gut decision. This affirmed my feeling that BMB was the best fit for me. The classes once I entered the department were better, but rushed. Truly, the knowledge acquired during your Ph.D. is earned through your own motivation to learn the background of your field and aided by the skills that were honed over my first two years here. Most importantly, the department classes taught me habits that have served me well in writing, and critically evaluating experiments and papers. This is of course not a practice that can be learned only through reading and writing, but requires quite a bit of hands on experience as well. Three of my four lab rotations taught me more than anything, what not to do. I knew that I would need to complete at least three to find my permanent home, but I was lucky enough to find the lab that I am currently in on the first try. I was also spoiled, and no other lab afterwards would do, but funding was an issue. I had to do a fourth rotation, stalling for time, with my fingers crossed, hoping that a grant would come through, but also having to seriously think about trying to carve a gene therapy project out of another lab. Unfortunately I was left with few options; the mentor-student relationship that I wanted was here, but temporarily unavailable. It does not do my ideal concept of a mentor-student relationship justice to say that I wanted a mentor who was very hands-on, but I suppose that is the core of the success that I found in the Chan lab. All I can say is that people in science, myself included, are stranger than I originally thought, and despite the fact that I feel like I could make do in a less than ideal situation, all of my other rotations were too far below the “less than ideal” bar. Just as I have not once questioned my belonging in graduate school, I have not questioned my choice of lab when I was able to join my first pick in late November of my second year.

In fact, when I received the e-mail that the lab could take me, I was so excited that I e-mailed all my friends and called my parents. And I was doubly lucky, the grant that would fund my work was shared between Teh-sheng Chan and his wife Lillian, so I too, would be shared. I truly cherish the guidance that I receive from this phenomenal team. Because Lillian plays such a large role in the program we often discuss current issues. I’m flattered that my opinions are valued inside and outside the lab environment. My mentors are not only good scientists; they are good, courteous, conscientious people. This, more than anything, allows me to maintain a firm grasp on my belief that science is a joy during the rough patches, and makes the good days, great.

Much of the first few months in lab were taken up with department qualifiers; reviewing course work for the open book, two-day exam; and preparing my proposal for the oral. I refer to it as the “jumping through flaming hoops” period. Everyone involved including myself, my mentors and the university, have invested a great deal of time and money into my development as a graduate student. As such, I think that it would be a rare occasion to not pass the qualifiers, but it was time intensive. I was frankly more relieved than excited to have it behind me when I was admitted to candidacy.

My experiments have recently taken a turn for the better and my mentors and I have all realized there is an end in sight. I’m ready to launch my animal experiments. They will take a little less than a year, at which point I can begin writing my thesis. I’m excited to go to committee again and show them the progress I have made in the last year. I have only had one update meeting with them since my oral proposal. They are a very helpful, intelligent, knowledgeable group. I wouldn’t change a single member of my committee, but I had to realize at our last meeting that I couldn’t simply update them. It was disappointing to realize that no one had glanced through my original research plan before they came to the meeting. It’s not that I expected their worlds to revolve around my progress, but they hadn’t done an ounce of homework. As such, they are longer meetings than I would like because I need to reintroduce the background, but the meetings themselves are not highly stressful.

The only tangible, and unavoidable, drawback to graduate studies so far are my lack of publications. Sometimes when I look at my classmates who are publishing I feel discouraged. Yet, I know that I wouldn’t be happy with another project, and the nature of this project does not lend itself to publication along the way. I have what I feel will be one, huge paper at the end of my experiments. It will tell a wonderful and complete story, and I am proud of that. But, I believe that it has prevented me from receiving my own funding. It worries me that funding and awards will not be an obtainable possibility until my experiments are all but complete. If this really is the case outside of this small realm of research; the implications that it has on finding funding when I am on my own and trying to launch a new project are daunting. However, this is a milestone that I know I will overcome should I encounter it. I cannot foresee being better prepared somewhere other than UTMB. I have blossomed personally and professionally here. I can only hope that my confidence in my future success is realized.

Undergraduate Institution: Canisius College; Buffalo, NY

Age: 27

Gender: Female

Nationality: USA

|| GSBS Home || Return to Table of Contents || Back To Top ||

Charles Todd Davis
Experimental Pathology

When I was eleven I went on my first snow skiing trip to Colorado. It was amazing. 10,000 ft. tall mountains covered with snow. For a Southerner, it was a world away from 70˚ Decembers and hot sticky summers. For the next 15 years I would go back every chance I had. I’d go in the winter for skiing or in the summer for hiking and camping. I loved the mountains in the winter and the summers felt like heaven on earth: crisp, clean air and huge blue skies. Every time I visited, I promised myself that I would move there some day. That opportunity finally presented itself four years ago when I was deciding on graduate schools to get a Ph.D. It was everything I had worked so hard to achieve: a great Ph.D. program in the perfect location. Fast forward four years later… This morning I woke up, broke a sweat on the way to my car, killed a mosquito or two that flew in the car with me, and drove forty-five minutes on I-45 from Houston to Galveston. Later that afternoon I did the same thing, just in the reverse order.

When I accepted an invitation to do my graduate studies at the University of Texas Medical Branch (UTMB) I did not foresee the two hour commute back and forth on the “scenic” Gulf Freeway. My fiancé and I thought that finding a teaching job on the island would not be a problem. Three months after she moved to Galveston, she finally found one… in Houston. Nor did I appreciate the magnitude of the phrase “one hundred percent humidity” or “hurricane evacuation route”. Indeed, I admit that I was at once lured by the idea of living on an island with 30 miles of beaches, swimming in the surf, and sipping frozen drinks on the weekends. But it was not for the sun and sand that I gave up my chance to live on Mountain Time, and it has not been the allure of island life that has maintained my peace of mind.

For the uninitiated, let me just say that UTMB has one of the largest groups of tropical and emerging infectious disease scientists at any university in the United States, perhaps the world. Behind this critical mass of researchers follows millions of dollars of funding, decades of expertise, and lots and lots of viruses (the kind you study of course). When I began my search for places to get my Ph.D. the search included some very well-respected universities. The name UTMB was new to me, but the reputation of the scientists working there were not. It took little encouragement from faculty members at the university where I did my masters degree to decide to apply. When I got around to looking for initial faculty contacts I was surprised to find out how many people were doing exactly the type of research that I was interested in. After sending out a few letters to faculty, I immediately realized what all the fuss was about. Everyone had great projects, plenty of lab space, and long-term grant support that would secure funding of student stipends. A quick database search for research publications of the faculty members made it even clearer that UTMB had established itself as a major player in the study of infectious disease. While the same could be said for many of the other universities for which I applied, the research productivity, grant support, resources, and personnel just didn’t add up to that put on the table by UTMB.

My first visit to the island really sealed the deal. After being flown in and put up at a very nice hotel, what impressed me most about the university was talking with all of the people whose research efforts I had been hearing about. The interview process was a breath of fresh air after being invited to universities by a single person for a single interview and for a single laboratory position. This was certainly not the case as I learned more about UTMB’s unique first year Basic Biomedical Science Curriculum (BBSC) and the opportunity to do lab rotations with many different mentors and in many different departments. The single greatest asset to the Graduate School of Biomedical Science (GSBS) is the fact that each student is brought into the University by an overarching authority, rather than a single department or much less a single person. This gives students the freedom to choose from a number of faculty mentors. When traveling to UTMB for the first time, I was under no pressure to meet a single person with whom I would spend the next several years working under. At UTMB you have the opportunity to meet many people with whom you may work for, and best of all, you have a choice in the matter. So when I found out that I had been accepted to UTMB it did not take much reflection to make a decision about where I would spend the next several years of my life. Colorado would have to wait.

The first year in the BBSC was difficult. Having not had courses in Biochemistry and very little Molecular Genetics, I was especially stressed by the work load. Help from students that had backgrounds in these courses and from faculty and tutors made the classes bearable. I was very focused on doing research in arthropod-borne virus studies so the integrative BBSC curriculum did not change my perspective on what I wanted to study, but it did broaden my outlook on the many different approaches that one might take to study those types of viruses. I ultimately chose the Department of Pathology because I really wanted to study infectious diseases and the Experimental Pathology program is one of the truly unique graduate programs for the study of tropical and emerging diseases. I really enjoyed the personnel in the department as well. The students and postdocs were very hard-working, the faculty very accomplished, and the administrators extremely helpful. The curriculum of the department was good because it gave me the freedom to choose the courses that I wanted to take rather than having all the courses selected by the department. While of course some courses were mandatory, the department placed a lot of emphasis on elective courses. This way I could take courses offered by other departments and not be constrained by being “forced” to take classes that I had already taken or didn’t feel that I needed to take.

Choosing rotations was a very natural experience for me. Because of my master’s degree background, I knew that I wanted to study vector-borne viruses. For most of the universities that I had considered, this would have meant choosing from three or four labs. But at UTMB this meant having a choice to rotate through as many as ten different labs. Because of this special scenario, the rotations meant not so much having to do decide what I wanted to do my dissertation studies on, but which lab I felt the most at home in. Again, because the GSBS was paying my first year stipend I was free to try many different labs and never felt pressure from any single mentor to choose their lab. I knew I was looking for a mentor that had a track record of productivity and who was motivated, but I also wanted someone that had a “laid-back” personality. I really wanted to find someone that I felt comfortable being around. It was also important that I found someone that would be open to my ideas, but that had several on-going projects that were of interest to me so that I could jump into an existing project and then run with my own ideas about how to make it a success. Fortunately for me, I had no trouble finding this person and I don’t think this was a problem for many students.

One of the exceptional traits of my mentor was his ability to put my priorities above his own. This became apparent as I began the process of applying for candidacy. My mentor made sure that I had enough time away from the lab to complete my course work and to do well on the qualifying exams. Although they were stressful, my mentor was always behind me and took the time to make sure that I was not too stressed-out by the process. After the qualifying exams were over, my mentor took the time to help me pick my committee members and to help in the preparation of my dissertation proposal. He really pushed me to finish this process as early as possible and encouraged me to publish my first paper before entering candidacy so that it would be clear to my committee that I was ready to begin my dissertation research phase. Not only was my mentor helpful in this regard, but the program director was also very supportive in terms of stress management and prioritizing my efforts. Other faculty members also lent a hand whenever possible. This feeling of encouragement and motivation from my mentor and other faculty has been evident during the course of my dissertation studies as well, and now that I have begun to focus solely on my dissertation research I am thankful of the flexibility that I was afforded during the first two years of my graduate studies. I have also been impressed by the availability of intramural grant opportunities from the University. My mentor and other faculty have been extremely helpful in helping me to write, apply for, and acquire several of those grants. They have also been very supportive and understanding of the importance of traveling to conferences to present my research and to network with scientists outside of UTMB. I have also been very satisfied by the resources available to me, not only in the lab, but also in the department, and university as a whole. I would also note that the experience and technical skills of the postdocs at UTMB are exceptional and are an integral part of the research machinery at the University.

When I decided to become a scientist, in particular one interested in public health and infectious disease research, I did not fully appreciate the dedication that people have for this field. All of the faculty that I have come into contact with instill their own spirit of motivation and tireless work ethic into the students around them and make coming to work every day a more meaningful experience. The work environment is also refreshing. In the lab that I work in, we have people representing at least six different countries of origin. This encourages a level of social awareness that I did not always consider. I was suddenly introduced to a world of people and perspectives that were new and different, and at once interesting and inspirational. I began to realize the importance of exploring diversity as a means of not only enriching day to day life, but also gaining knowledge. I think this is really a prerequisite for the study of health science. As we are too often reminded, public health care problems are rarely resolved by the initiative of a single entity. In dealing with health care dilemmas, at either a local or global scale, partnerships between a number of disciplines, organizations, and most assuredly, a diverse group of people are essential. As a Ph.D. student in an infectious disease laboratory with co-workers from a variety of backgrounds, I‘ve come to understand the significance of working in a diverse environment. It has taught me the importance of research collaboration when addressing problems related to the spread and prevention of infectious diseases and has allowed me to make contacts with researchers from all over the world with whom I hope to sustain relationships with in the future.

Now that my graduate studies are coming to a close, the drive to and from Galveston reminds me of the reasons why I chose to come to UTMB in the first place and the reasons why I would recommend the university to anyone. Not only has the research experience been all I had hoped it would be, but the friends and colleagues that I have made will definitely be an attribute to my future life both personally and professionally. As I begin my search for places to do postdoctoral studies, I feel confident that I am prepared to take on research projects in many different fields of infectious disease and that I will be a valuable asset to any lab. Several students and postdocs that have left my lab have been able to find outstanding postdoctoral and faculty positions and have been heavily recruited because of their experience gained at UTMB. As the reputation the University flourishes, I have no doubt that I will be marketable as a researcher in the coming years. While I don’t think I will miss life on the island (and definitely not rush hour traffic on I-45) I will certainly miss the work environment and the people that make UTMB a truly unique university.

|| GSBS Home || Return to Table of Contents || Back To Top ||

 
 
 

| About GSBS | Prospective Students | Current Students | Programs and Curricula |
| Useful Links | Forms | Alumni and Friends | Site Map | Home | Contact | Search |

UTMB | Search | Directories | Toolbox | News | Employment | Sitemap | Compact with UT System
UT System | Privacy Policy | Reports to the State | Compact with Texans | Statewide Search

Send emails to the webmaster with questions or comments about this website.
To contact the Graduate School, send email to the
Graduate School or reach us by telephone at (409) 772-2665.
Copyright © 2001 The University of Texas Medical Branch.  Please review our
privacy policy and Internet Guidelines

301 University Boulevard   |   4.429 Levin Hall   |   Galveston, TX 77555-1050   |   Phone: (409) 772-2665   |   Fax: (409) 747-0772